Recombinant human RGS4 protein
RGS4 (regulator of G protein signaling 4) is a protein which regulates G protein signaling. Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. Recombinant human RGS4 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Specifications
Product Name Alternative
Regulator of G-protein signaling 4, DKFZp761F1924, MGC2124, MGC60244, RGP4, SCZD9
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 90% by SDS-PAGE
Molecular Weight
25.4 kDa (225aa) confirmed by MALDI-TOF
Additionnal Information
References & Citations
Chowdari K.V., et al. (2002) Hum. Mol. Genet. 11:1373-1380; ; Tu Y., et al (1999) J. Biol. Chem. 274:38260-38267
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 5mM DTT, 10% glycerol, 200 mM NaCl
Scientific Category
Signal Transduction
NCBI Accession Number
NP_005604
Uniprot Accession Number
P49798
Species
Human
AA Sequence
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