Recombinant human RGS4 protein

RGS4 (regulator of G protein signaling 4) is a protein which regulates G protein signaling. Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. Recombinant human RGS4 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Regulator of G-protein signaling 4, DKFZp761F1924, MGC2124, MGC60244, RGP4, SCZD9

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

25.4 kDa (225aa) confirmed by MALDI-TOF

Additionnal Information

RGS4, Regulator of G-protein signaling 4, DKFZp761F1924, MGC2124, MGC60244, RGP4, SCZD9, ATGP1160-10 µg, ATGP1160-20 µg, ATGP1160-50 µg, ATGP1160-100 µg, ATGP1160-250 µg, ATGP1160-500 µg, ATGP1160-1 mg, ATGP1160-10, ATGP1160-20, ATGP1160-50, ATGP1160-100, ATGP1160-250, ATGP1160-500, ATGP1160-1

References & Citations

Chowdari K.V., et al. (2002) Hum. Mol. Genet. 11:1373-1380; ; Tu Y., et al (1999) J. Biol. Chem. 274:38260-38267

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 5mM DTT, 10% glycerol, 200 mM NaCl

Scientific Category

Signal Transduction

NCBI Accession Number

NP_005604

Uniprot Accession Number

P49798

Species

Human

AA Sequence

MCKGLAGLPA SCLRSAKDMK HRLGFLLQKS DSCEHNSSHN KKDKVVICQR VSQEEVKKWA ESLENLISHE CGLAAFKAFL KSEYSEENID FWISCEEYKK IKSPSKLSPK AKKIYNEFIS VQATKEVNLD SCTREETSRN MLEPTITCFD EAQKKIFNLM EKDSYRRFLK SRFYLDLVNP SSCGAEKQKG AKSSADCASL VPQCA