Recombinant human ARL4/ARL4A protein

ARL4A, also known as ADP-ribosylation factor-like protein 4A, is a member of the ARF-like protein (ARL) subfamily of small GTPases. It is most closely related to ARL6 and ARL7. unlike ARFs, ARL4 does not activate the cholera toxin ADP-ribosyltranferase. This protein may play a role in neurogenesis during embryonic development and somitogenesis in the early stages of adult spermatogenesis. Recombinant human ARL4A protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Product Specifications

Product Name Alternative

ADP-ribosylation factor-like protein 4A, ARL4, ADP ribosylation factor like GTPase 4A

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

0.25 mg/mL (determined by Bradford assay)

Purity

> 90% by SDS-PAGE

Molecular Weight

24.7 kDa (220aa) confirmed by MALDI-TOF

Additionnal Information

ARL4A, ADP-ribosylation factor-like protein 4A, ARL4, ATGP1151-10 µg, ATGP1151-20 µg, ATGP1151-50 µg, ATGP1151-100 µg, ATGP1151-250 µg, ATGP1151-500 µg, ATGP1151-1 mg, ATGP1151-10, ATGP1151-20, ATGP1151-50, ATGP1151-100, ATGP1151-250, ATGP1151-500, ATGP1151-1

References & Citations

Lin CY. et al. (2000) J. Biol. Chem. 275:37815-23.; ; Schurmann A. et al. (1994) J. Biol. Chem. 269: 15683-8.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT

Scientific Category

Signal Transduction

NCBI Accession Number

NP_005729.1

Uniprot Accession Number

P40617

Species

Human

AA Sequence

MGNGLSDQTS ILSNLPSFQS FHIVILGLDC AGKTTVLYRL QFNEFVNTVP TKGFNTEKIK VTLGNSKTVT FHFWDVGGQE KLRPLWKSYT RCTDGIVFVV DSVDVERMEE AKTELHKITR ISENQGVPVL IVANKQDLRN SLSLSEIEKL LAMGELSSST PWHLQPTCAI IGDGLKEGLE KLHDMIIKRR KMLRQQKKKR