Recombinant human GABARAP protein

GABARAP, also known as gamma-aminobutyric acid receptor-associated protein, is highly positively charged in its N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. This protein clusters neurotransmitter receptors by mediating interaction with the cytoskeleton. Recombinant GABARAP protein was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

Gamma-aminobutyric acid receptor-associated protein, MM46, Gamma-aminobutyric acid receptor-associated protein FLC 3B, FLC3B, FLJ25768, GABA (A) receptor associated protein, Gamma aminobutyric acid receptor associated protein, MGC120154, MGC120155, MM 46, MM46.

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Purity

> 95% by SDS-PAGE

Molecular Weight

16 kDa (137aa) confirmed by MALDI-TOF

Additionnal Information

GABARAP, Gamma-aminobutyric acid receptor-associated protein, MM46, Gamma-aminobutyric acid receptor-associated protein FLC 3B, FLC3B, FLJ25768, GABA (A) receptor associated protein, Gamma aminobutyric acid receptor associated protein, MGC120154, MGC120155, MM 46, MM46., ATGP0465-10 µg, ATGP0465-20 µg, ATGP0465-50 µg, ATGP0465-100 µg, ATGP0465-250 µg, ATGP0465-500 µg, ATGP0465-1 mg, ATGP0465-10, ATGP0465-20, ATGP0465-50, ATGP0465-100, ATGP0465-250, ATGP0465-500, ATGP0465-1

References & Citations

Stangler T., et al. (2002) J Biol Chem. 277 (16) :13363-6.

Other References

Kondo N et al., The autophagy component LC3 regulates lymphocyte adhesion via LFA1 transport in response to outside-in signaling. (Nat Commun. 2025) {https://pubmed.ncbi.nlm.nih.gov/39905041/}

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol 0.2M NaCl

Scientific Category

Neuroscience

NCBI Accession Number

NP_009209

Uniprot Accession Number

O95166

Species

Human

AA Sequence

MGSSHHHHHH SSGLVPRGSH MKFVYKEEHP FEKRRSEGEK IRKKYPDRVP VIVEKAPKAR IGDLDKKKYL VPSDLTVGQF YFLIRKRIHL RAEDALFFFV NNVIPPTSAT MGQLYQEHHE EDFFLYIAYS DESVYGL