Recombinant human CCL28/MEC protein

CCL28, also known as chemokine (C-C motif) ligand 28 or mucosae-associated epithelial chemokine (MEC), belongs to the subfamily of small cytokine CC proteins. CCL28 is expressed by columnar epithelial cells in the gut, lung, breast and the salivary glands and drives the mucosal homing of T and B lymphocytes that express CCR10, and the migration of eosinophils expressing CCR3. This chemokine is constitutively expressed in the colon, but its levels can be increased by pro-inflammatory cytokines and certain bacterial products implying a role in effector cell recruitment to sites of epithelial injury. Recombinant CCL28 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Product Specifications

Product Name Alternative

C-C motif chemokine ligand 28, Mucosae-associated epithelial chemokine, MEC, Protein CCK1, Small-inducible cytokine A28, SCYA28, CCK1

Expression System

E.coli

Antigen Species

Human

Tag

His-Tag

Applications

SDS-PAGE

Concentration

1 mg/mL (determined by Bradford assay)

Endotoxin

< 1 EU per 1ug of protein (determined by LAL method)

Purity

> 90% by SDS-PAGE

Molecular Weight

14.3 kDa (126aa) confirmed by MALDI-TOF

Additionnal Information

CCL28, Chemokine (C-C motif) ligand 28, CCK1, MEC, SCYA28, Chemokine (C-C motif) ligand 28, CCL28, CC chemokine CCL28, mucosae-associated epithelial chemokine, small inducible cytokine subfamily A (Cys-Cys) member 28, small inducible cytokine A28, ATGP0387-10 µg, ATGP0387-20 µg, ATGP0387-50 µg, ATGP0387-100 µg, ATGP0387-250 µg, ATGP0387-500 µg, ATGP0387-1 mg, ATGP0387-10, ATGP0387-20, ATGP0387-50, ATGP0387-100, ATGP0387-250, ATGP0387-500, ATGP0387-1