Talatisamine
Talatisamine, a aconitum alkaloid, is specific K+ channel blocker. Talatisamine attenuates beta-amyloid oligomers induced neurotoxicity in cultured cortical neurons[1].
Product Specifications
CAS Number
20501-56-8
UNSPSC
12352005
Target
Potassium Channel
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/talatisamine.html
Concentration
10mM
Purity
99.77
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
CO[C@@H]1C(C(N(CC)C2)C3C4)([C@@](C[C@@]5([H])[C@@H]6O)([H])[C@@]6([H])[C@@]3(C[C@@H]5OC)O)[C@@]4([H])[C@@]2(COC)CC1
Molecular Formula
C24H39NO5
Molecular Weight
421.57
References & Citations
[1]Wang Y, et al. The newly identified K+ channel blocker talatisamine attenuates beta-amyloid oligomers induced neurotoxicity in cultured cortical neurons. Neurosci Lett. 2012 Jun 19;518 (2) :122-7.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR15196850 1 Vial
Lentiviral mouse Apol7c shRNA (UAS) - Lentiviral mouse Apol7c shRNA (UAS, iRFP) (25)
Sign In for Pricing
View Details 
MBS8124232-01 0.1 mg
SARS-CoV-2 (BA.2.75) Spike S1+S2 trimer Protein (ECD, His Tag)
Sign In for Pricing
View Details MBS8124232-02 5x 0.1 mg
SARS-CoV-2 (BA.2.75) Spike S1+S2 trimer Protein (ECD, His Tag)
Sign In for Pricing
View Details