DAB2 rabbit pAb
Product Specifications
Background
This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Product Name Alternative
Disabled homolog 2 (DOC-2) (Differentially-expressed protein 2)
Gene ID
1601
Swiss Prot
P98082
Cross Reactivity
Human; Mouse; Rat
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Dilution
WB 1:500-2000
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.333% sodium azide.
Molecular Weight
85
Storage Conditions
-20°C/1 year
Protein Weight
85
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15168190 1 Vial
Lentiviral mouse Dhrs13 shRNA (UAS) - Lentiviral mouse Dhrs13 shRNA (UAS, GFP) plasmid
Ask
View Details 
