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SRF (phospho Ser77) Polyclonal Antibody

Product Specifications

Background

Serum response factor (SRF) Homo sapiens This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs) . Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]

Product Name Alternative

SRF; Serum response factor; SRF

Gene ID

6722

Swiss Prot

P11831

Cross Reactivity

Human; Mouse

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC-p; IF (paraffin section) ; ELISA

Dilution

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Molecular Weight

52

Storage Conditions

-20°C/1 year

Protein Weight

52

Available Sizes

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