ETL Polyclonal Antibody

Developmental stage:Up-regulated in the adult heart., domain:The transmembrane domain is not required for cleavage, but it is required for dimer formation., function:Could be involved in cardiac development., PTM:Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit., similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily., similarity:Contains 1 GPS domain., similarity:Contains 2 EGF-like domains., subunit:Forms a heterodimer, consisting of a large extracellular region (alpha subunit) non-covalently linked to a seven-transmembrane moiety (beta subunit) . Forms stable dimer at the cells surface., tissue specificity:Mainly expressed in smooth muscle.