AZ'6421
AZ'6421 acts as Protcolysis Targeting Chimera (PROTAC) to selectively degrade estrogen receptor alpha. AZ'6421 has a potent anti-tumour effect to inhibit the uncontrolled cellular proliferation which arises from malignant disease. AZ'6421 can be used for the research of cancer such as breast cancer[1].
Product Specifications
CAS Number
2361115-35-5
UNSPSC
12352005
Target
Estrogen Receptor/ERR; PROTACs
Type
Reference compound
Related Pathways
PROTAC; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/az-6421.html
Purity
98.13
Solubility
DMSO : ≥ 100 mg/mL
Smiles
Molecular Formula
C52H65F3N6O7S
Molecular Weight
975.17
References & Citations
[1]Bin Yang, et al. Compounds and their use in treating cancer. Patent WO2019123367A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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