TIRAP Recombinant Antibody, PerCP Conjugated
Product Specifications
Background
Adapter involved in TLR2, TLR4 and RAGE signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha (TNF) and interleukin-6 (IL6) .
Synonyms
MAL; Wyatt.
Gene ID
114609
Swiss Prot
P58753
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
TIRAP
Clonality
Recombinant
Isotype
IgG
Conjugation
PerCP
Source
KLH conjugated synthetic peptide derived from human TIRAP
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
482nm/677nm
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
114609
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