MDH1-IN-1
MDH1-IN-1 (Compound 5i) is a potent inhibitor of MDH1 with an IC50 of 6.79 μM. MDH1-IN-1 has the potential for the research of cancer diseases[1].
Product Specifications
CAS Number
2143463-31-2
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mdh1-in-1.html
Purity
99.97
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(OC)C1=CC=CC(NC(COC2=CC=C(CCCCC)C=C2)=O)=C1
Molecular Formula
C21H25NO4
Molecular Weight
355.43
References & Citations
[1]Naik R, et al. Methyl 3- (3- (4- (2,4,4-Trimethylpentan-2-yl) phenoxy) -propanamido) benzoate as a Novel and Dual Malate Dehydrogenase (MDH) 1/2 Inhibitor Targeting Cancer Metabolism. J Med Chem. 2017;60 (20) :8631-8646.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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