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CaMKII delta Recombinant Antibody, PE-Cy5.5 Conjugated

Product Specifications

Background

Calcium/calmodulin-dependent protein kinase involved in the regulation of Ca2+ homeostatis and excitation-contraction coupling (ECC) in heart by targeting ion channels, transporters and accessory proteins involved in Ca2+ influx into the myocyte, Ca2+ release from the sarcoplasmic reticulum (SR), SR Ca2+ uptake and Na+ and K+ channel transport. Targets also transcription factors and signaling molecules to regulate heart function. In its activated form, is involved in the pathogenesis of dilated cardiomyopathy and heart failure.

Synonyms

CAM kinase 2 delta; CAM kinase II delta; CaM kinase II delta subunit; CaM kinase II subunit delta; CAMK 2d; CaMK-II delta subunit; CAMK2D; CAMKI.

Gene ID

817

Swiss Prot

Q13557

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human

Target

CaMKII delta

Clonality

Recombinant

Isotype

IgG

Conjugation

PE-Cy5.5

Source

KLH conjugated synthetic peptide derived from human CaMKII delta

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

488nm/694nm

Concentration

Lot dependent

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

817

Predicted Cross Reactivity

Mouse, Rat

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