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PRNP Recombinant Antibody

Product Specifications

Background

The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity) . Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro) .

Synonyms

Major prion protein, ASCR, PrP27-30, PrP33-35C, CD_antigen: CD230, PrP, PRNP

Gene ID

5621

Swiss Prot

P04156

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

PRNP

Clonality

Recombinant

Isotype

IgG

Conjugation

Unconjugated

Source

C terminal human Prion protein

Applications

WB, FCM, IF (ICC), IHC

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100), IF (ICC) (1:50-200), IHC ()

Buffer

0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

5621

Available Sizes

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