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Kininogen-1 light chain Antibody, APC Conjugated

Product Specifications

Background

This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK) . HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009].

Synonyms

Alpha 2 thiol proteinase inhibitor; HMW Kininogen light Chain; Alpha-2-thiol proteinase inhibitor; Fitzgerald factor; High molecular weight kininogen; HMWK; Ile-Ser-Bradykinin; Kallidin I; Kallidin II; Kininogen 1; KNG1; KNG1_HUMAN; Low molecular weight growth-promoting factor; Williams-Fitzgerald-Flaujeac factor.

Gene ID

3827

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

551-644/644

Target

Kininogen-1 light chain

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC

Source

KLH conjugated synthetic peptide derived from human HMW Kininogen-1 light chain

Applications

IF

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

1µg/µl

Dilution

IF (IF=1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

3827

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