ARMCX3 Antibody (C-term) [APR31695G]
Product Specifications
Synonyms
Armadillo repeat-containing X-linked protein 3, ARM protein lost in epithelial cancers on chromosome X 3, Protein ALEX3, ARMCX3, ALEX3
Gene Name
ARMCX3
Gene ID
51566
UniProt
Q9UH62
Chromosomal Location
Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q8BHS6}; Single-pass membrane protein. Cytoplasm {ECO:0000250|UniProtKB:Q8BHS6}. Nucleus {ECO:0000250|UniProtKB:Q8BHS6}
Applications
WB
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Regulates mitochondrial aggregation and transport in axons in living neurons. May link mitochondria to the TRAK2-kinesin motor complex via its interaction with Miro and TRAK2. Mitochondrial distribution and dynamics is regulated through ARMCX3 protein degradation, which is promoted by PCK and negatively regulated by WNT1. Enhances the SOX10-mediated transactivation of the neuronal acetylcholine receptor subunit alpha-3 and beta-4 subunit gene promoters.
Molecular Weight
42501
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ARMCX3 Antibody (C-term) [APR31695G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=51566
Uniprot URL
https://www.uniprot.org/uniprot/Q9UH62
Available Sizes
Curated Selection
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