COPS8 Polyclonal Antibody, APC Conjugated
Product Specifications
Background
The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008].
Synonyms
COP9 homolog; COP9 signalosome complex subunit 8; Cops8; CSN8; CSN8_HUMAN; hCOP9; JAB1 containing signalosome subunit 8; JAB1-containing signalosome subunit 8; SGN8; Signalosome subunit 8.
Gene ID
10920
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
101-200/209
Target
COPS8
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from human COPS8
Applications
WB, IF (IHC-P)
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
10920
Curated Selection
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