Oclacitinib maleate
Oclacitinib maleate is a selective Janus kinase (JAK) inhibitor with IC50 values of 10-99 nM against JAK family members. It potently inhibits JAK1-dependent cytokine signaling and demonstrates high selectivity over other kinases. This compound is widely used in preclinical research for investigating allergic dermatitis and pruritus in both in vitro and in vivo models.
Product Specifications
CAS Number
1640292-55-2
Product Name Alternative
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.17% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (7.28 mM) ; Ethanol:83 mg/mL (183.02 mM) ; H2O:15 mg/mL (33.08 mM) ; DMSO:83 mg/mL (183.02 mM)
Smiles
OC (=O) \C=C\C (O) =O.CNS (=O) (=O) C[C@H]1CC[C@@H] (CC1) N (C) c1ncnc2[nH]ccc12
Molecular Formula
C15H23N5O2S·C4H4O4
Molecular Weight
453.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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