APLP2 Polyclonal Antibody, APC Conjugated

APLP2 is a human sperm membrane protein which contains a segment with high homology to the transmembrane-cytoplasmic domains of APP found in brain plaques of Alzheimer disease patients. The human amyloid precursor-like protein APLP2 is a highly conserved homolog of a sequence-specific DNA-binding mouse protein with an important function in the cell cycle. The gene which encodes APLP2 maps to human chromosome 11q24.May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3' (CDEI box) . Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein.

Amyloid beta A4 precursor like protein 2; Amyloid like protein 2; amyloid precursor protein homolog HSD2; Amyloid protein homolog; Amyloid-like protein 2; APLP-2; Aplp2; APLP2_HUMAN; APPH; APPL2; CDEBP; CDEI box binding protein; CDEI box-binding protein.