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GPX4-IN-5

Product Specifications

CAS Number

2922824-09-5

Target

GPX

Applications

Immunology & Inflammation

Smiles

COC1=CC (N (C2=CC3=C (OCCO3) C=C2) C (CCl) =O) =CC (OC) =C1F

Molecular Formula

C18H17ClFNO5

Additionnal Information

GPX4-IN-5 covalently inhibits GPX4 with an IC50 of 0.12 μM. This compound induces ferroptosis and exhibits anti-tumor activity. It has potential applications in triple-negative breast cancer (TNBC) research.

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