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RETF-4NA

RETF-4NA, a chymase-specific substrate, is a sensitive and selective substrate for chymase when free or bound to α2M[1][2].

Product Specifications

CAS Number

1160928-63-1

UNSPSC

12352209

Target

Biochemical Assay Reagents

Type

Peptides

Related Pathways

Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/retf-4na.html

Solubility

H2O

Smiles

O=C(NC1=CC=C(C=C1)[N+]([O-])=O)[C@@H](NC([C@H]([C@H](O)C)NC([C@H](CCC(O)=O)NC([C@@H](NC(C)=O)CCCNC(N)=N)=O)=O)=O)CC2=CC=CC=C2

Molecular Formula

C32H43N9O10

Molecular Weight

713.74

References & Citations

[1]Wilfred W Raymond, et al. Alpha 2-macroglobulin Capture Allows Detection of Mast Cell Chymase in Serum and Creates a Reservoir of Angiotensin II-generating Activity. J Immunol. 2009 May 1;182 (9) :5770-7.|[2]Katariina Maaninka, et al. Human Mast Cells Arise From a Common Circulating Progenitor. J Allergy Clin Immunol. 2013 Aug;132 (2) :463-9.e3.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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