MAGEA5 Polyclonal Antibody, APC Conjugated

MAGEA5 is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This MAGEA gene encodes a protein that is C-terminally truncated compared to other family members, and this gene can be alternatively interpreted to be a pseudogene.

Cancer/testis antigen 1.5; Cancer/testis antigen family 1 member 5; CT1.5; MAGE 5 antigen; MAGE 5a antigen; MAGE 5b antigen; MAGE5; MAGEA4; Melanoma antigen family A 5; Melanoma associated antigen 5; MGC129526; MAGA5_HUMAN.