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(Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat)

Product Specifications

UNSPSC Description

(Asn10,Leu11,D-Trp12)-pTH-Related Protein (7-34) amide (human, mouse, rat) is a potent PTH-1R antagonist[1][2].

Target Antigen

PTHR

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/asn10-leu11-d-trp12-pth-related-protein-7-34-amide-human-mouse-rat.html

Purity

98.56

Solubility

DMSO : 20 mg/mL (ultrasonic)

Smiles

NC([C@H](C)NC([C@H]([C@H](O)C)NC([C@H](CC1=CN=CN1)NC([C@H]([C@@H](C)CC)NC([C@H](CCC(O)=O)NC([C@H](C)NC([C@H]([C@@H](C)CC)NC([C@H](CC(C)C)NC([C@H](CC2=CN=CN2)NC([C@H](CC3=CN=CN3)NC([C@H](CC(C)C)NC([C@H](CC4=CC=CC=C4)NC([C@H](CC5=CC=CC=C5)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@H](CC(O)=O)NC([C@H](CCC(N)=O)NC([C@H]([C@@H](C)CC)NC([C@H](CO)NC([C@H](CCCCN)NC([C@H](NC([C@H](CC(C)C)NC([C@H](CC(N)=O)NC([C@@H](NC([C@H](CC(C)C)NC([C@@H](N)CC(C)C)=O)=O)CC6=CN=CN6)=O)=O)=O)CC7=CNC8=CC=CC=C78)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Weight

3478.06

References & Citations

[1]Nutt RF, et al. Removal of partial agonism from parathyroid hormone (PTH)-related protein-(7-34)NH2 by substitution of PTH amino acids at positions 10 and 11. Endocrinology. 1990 Jul;127(1):491-3. |[2]Portal-Núñez S, et al. Parathyroid hormone-related protein exhibits antioxidant features in osteoblastic cells through its N-terminal and osteostatin domains. Bone Joint Res. 2018 Jan;7(1):58-68.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-P4385/Asn10-Leu11-D-Trp12-pTH-Related-Protein-7-34-amide-human-mouse-rat-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P4385/Asn10-Leu11-D-Trp12-pTH-Related-Protein-7-34-amide-human-mouse-rat-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

129622-68-0

Available Sizes

Curated Selection

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