CD44v3 Polyclonal Antibody, Cy5 Conjugated
Product Specifications
Background
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs) . This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]
Synonyms
CD44 antigen; CD44 molecule; CD44v3; Heparan sulfate proteoglycan; IN; MUTCH 1; Phagocytic glycoprotein I.
Gene ID
960
Swiss Prot
P16070
Host
Rabbit
Cross Reactivity
Human
Immunogen
161-260/493
Target
CD44v3
Clonality
Polyclonal
Isotype
IgG
Conjugation
Cy5
Source
KLH conjugated synthetic peptide derived from human MUTCH 1
Applications
FCM, IF (ICC), IF
Purification
Purified by Protein A.
Excitation Emission
625,650nm/670nm
Concentration
1µg/µl
Dilution
FCM (1:20-100), IF (ICC) (1:50-200), IF ()
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
960
Curated Selection
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