Synaptotagmin 1 Polyclonal Antibody, AbBy Fluor™ 488 Conjugated

Product Specifications

Background

May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca (2+) -dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca (2+) -independent manner; these are neurexins, syntaxin and AP2.

Synonyms

P65; SYT; SVP65; Synaptotagmin-1; Synaptotagmin I; SytI; SYT1

Gene ID

6857

Swiss Prot

P21579

Cellular Locus

Secreted, Extracellular matrix

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

165-260/422

Target

Synaptotagmin 1

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 488

Source

KLH conjugated synthetic peptide derived from human Synaptotagmin 1

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

499nm/519nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Specificity

This antibody will cross-react with Synaptotagmin 2 and

Gene ID URL

6857

Predicted Cross Reactivity

Dog, Cow, Pig, Chicken, Rabbit

Available Sizes

Curated Selection

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