CD33 Polyclonal Antibody, PE Conjugated
Product Specifications
Background
Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase (s) via their SH2 domain (s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro) .
Synonyms
P67; SIGLEC3; SIGLEC-3; Myeloid cell surface antigen CD33; Sialic acid-binding Ig-like lectin 3; gp67; CD33
Gene ID
945
Swiss Prot
P20138
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human
Immunogen
261-364/364
Target
CD33
Clonality
Polyclonal
Isotype
IgG
Conjugation
PE
Source
KLH conjugated synthetic peptide derived from human CD33
Applications
WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
496,564nm/578nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
945
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR15284537 1 Vial
Lentiviral mouse Mxd1 shRNA (UAS) - Lentiviral mouse Mxd1 shRNA (UAS) (25)
Sign In for Pricing
View Details 
K0361908 1.0 µg DNA
CAPS2 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)
Sign In for Pricing
View Details 031143-AP 200 µL
Myc-Tag (c-myc, myc-1 epitope tag) (AP) discontinued
Sign In for Pricing
View Details 
CSB-EP009443HU1-01 10 µg
Recombinant Human Gap junction alpha-1 protein (GJA1), partial
Sign In for Pricing
View Details