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Anti-Mouse/Rat/Human CCL2/MCP-1 Antibody (2H5)

Selected Variant

HY-P990297-01

Size: 1 mg

Anti-Mouse/Rat/Human CCL2/MCP-1 Antibody (2H5) is an anti-mouse/rat/human CCL2/MCP-1 IgG monoclonal antibody. Anti-Mouse/Rat/Human CCL2/MCP-1 Antibody (2H5) can reverse the immunosuppressive microenvironment by blocking the CCL2 signaling pathway. Anti-Mouse/Rat/Human CCL2/MCP-1 Antibody (2H5) can reduce the secretion of IFN-γ and the infiltration of macrophages. CCL2/MCP-1 Antibody (2H5) can reduce the amount of HIV virus by increasing the proportion of T cells. Anti-Mouse/Rat/Human CCL2/MCP-1 Antibody (2H5) can be used for researches on inflammation conditions, virus infection and cancer such as inflammatory bowel disease (IBD), hepatocellular carcinoma (HCC) and HIV[1][2][3][4][5].

Product Specifications

CAS Number

9007-83-4

UNSPSC

12352203

Target

CCR; HIV

Type

Inhibitory Antibodies

Related Pathways

Anti-infection; GPCR/G Protein; Immunology/Inflammation

Field of Research

Cancer; Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-mouse-rat-human-ccl2-mcp-1-antibody-2h5.html

Purity

95.00

Solubility

10 mM in DMSO

Smiles

[Anti-Mouse/Rat/HumanCCL2/MCP-1Antibody(2H5)]

Molecular Weight

(150 kDa)

References & Citations

[1]Sayed IM, et al. Host engulfment pathway controls inflammation in inflammatory bowel disease. FEBS J. 2020 Sep;287 (18) :3967-3988.|[2]Cui R, et al. Human mesenchymal stromal/stem cells acquire immunostimulatory capacity upon cross-talk with natural killer cells and might improve the NK cell function of immunocompromised patients. Stem Cell Res Ther. 2016 Jul 7;7 (1) :88.|[3]Ma Y, et al. Microglia LILRB4 upregulation reduces brain damage after acute ischemic stroke by limiting CD8+ T cell recruitment. J Neuroinflammation. 2024 Aug 31;21 (1) :214.|[4]Du Y, et al. ASH1L in Hepatoma Cells and Hepatic Stellate Cells Promotes Fibrosis-Associated Hepatocellular Carcinoma by Modulating Tumor-Associated Macrophages. Adv Sci (Weinh) . 2024 Dec;11 (45) :e2404756.|[5]Packard TA, et al. CCL2: a Chemokine Potentially Promoting Early Seeding of the Latent HIV Reservoir. mBio. 2022 Oct 26;13 (5) :e0189122.

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4°C for 2 years, do not freeze

Scientific Category

Inhibitory Antibodies

Clinical Information

No Development Reported

Available Sizes

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