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Anti-ZPI/SERPINA10 Antibody Picoband®

Boster Bio Anti-ZPI/SERPINA10 Antibody Picoband® catalog # A05576-2. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

The protein encoded by this gene belongs to the serpin family. It is predominantly expressed in the liver and secreted in plasma. It inhibits the activity of coagulation factors Xa and XIa in the presence of protein Z, calcium and phospholipid. Mutations in this gene are associated with venous thrombosis. Alternatively spliced transcript variants have been found for this gene.

Synonyms

Phosphopantothenate--cysteine ligase, Phosphopantothenoylcysteine synthetase, PPC synthetase, PPCS, COAB

Gene Name

SERPINA10

Gene ID

51156

UniProt

Q9UK55

Host

Rabbit

Reactivity

Human, Mouse, Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human ZPI/SERPINA10 recombinant protein (Position: L128-E427) .

Clonality

Polyclonal

Tissue Specificity

Expressed in heart, placenta, skeletal muscle kidney, pancreas, spleen, prostate, testis, ovary, ileum and colon. Expressed in lung endothelial and smooth muscle cells (at protein level) .

Applications

WB, Flow Cytometry, ELISA

Field of Research

Amino Acid Metabolism, Amino Acids, Cofactors, Vitamins/Minerals, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Signal Transduction, Vitamins/Minerals

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Catalyzes the first step in the biosynthesis of coenzyme A from vitamin B5, where cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine.

References & Citations

1. Han, X., Fiehler, R., Broze, G. J., Jr. Isolation of protein Z-dependent plasma protease inhibitor. Proc. Nat. Acad. Sci. 95: 9250-9255, 1998. 2. Han, X., Huang, Z. F., Fiehler, R., Broze, G. J., Jr. The protein Z-dependent protease inhibitor is a serpin. Biochemistry 38: 11073-11078, 1999. 3. New, L., Liu, K., Kamali, V., Plowman, G., Naughton, B. A., Purchio, A. F. cDNA cloning of rasp-1, a novel gene encoding a plasma protein associated with liver regeneration. Biochem. Biophys. Res. Commun. 223: 404-412, 1996.

Storage Conditions

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Calculated Molecular Weight

48608 MW

Observed Molecular Weight

71 kDa

Applications Notes

6

Gene Name Synonym

Phosphopantothenoylcysteine synthetase

Subcellular Location

Cytosol.

Protein Name

Serine protease HTRA3

Isotype

Rabbit IgG

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

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