VAMP1+VAMP2+VAMP3 Polyclonal Antibody
Product Specifications
Background
Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP) /synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation. [provided by RefSeq, Jul 2008].
Synonyms
Vesicle Associated Membrane Protein 1; DKFZp686H12131; SYB 1; SYB1; Synaptobrevin 1; Synaptobrevin1; Synaptobrevin-1; VAMP 1; VAMP-1; Vesicle associated membrane protein 1; Vesicle associated membrane protein 1 synaptobrevin 1; VAMP1_HUMAN; Vesicle-associated membrane protein 1; Vesicle Associated Membrane Protein 2; FLJ11460; RATVAMPB; RATVAMPIR; SYB; SYB2; Synaptobrevin 2; VAMP 2; VAMP-2; Vesicle associated membrane protein 2; Vesicle-associated membrane protein 2; VAMP2_HUMAN; Synaptobrevin-2; Vesicle Associated Membrane Protein 3; VAMP-3; VAMP 3; VAMP3; CEB; Cellubrevin; Synaptobrevin 3; Synaptobrevin-3; MGC108618; Vamp3; D130027G05Rik; VAMP3_HUMAN; Vesicle-associated membrane protein 3.
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
21-118/118
Target
VAMP1+VAMP2+VAMP3
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human VAMP-1+2+3
Applications
WB, ELISA, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Predicted Cross Reactivity
Dog, Cow, Pig, Horse, Chicken, Rabbit, GuineaPig
Curated Selection
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