HIV-1 inhibitor-21
Product Specifications
CAS Number
2554620-04-9
Target
HIV Protease|||Others
Related Pathways
Proteases/Proteasome|||Others|||Microbiology/Virology
Bioactivity
HIV-1 inhibitor-21 (compound 9b) is a potent inhibitor of HIV-1 non-nucleoside reverse transcriptase (RT) with an IC50 of 0.55 ?M. It inhibits both wild-type HIV-1 (EC50: 12.7 nM) and mutant virus strain K103N (EC50: 10.4 nM), demonstrating relatively low cytotoxicity (CC50 for MT-4: 10.2 ?M) .
Smiles
N(C=1C2=C(N=C(NC3=CC=C(C#N)C=C3)N1)C=C(OC)C(OC)=C2)C4=C(C)C=C(/C=C/C#N)C=C4C
Molecular Formula
C28H24N6O2
Molecular Weight
476.53
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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