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Orexin A Polyclonal Antibody, PerCP Conjugated

Product Specifications

Background

Orexin A (hypocretin 1) a 33 amino acid peptide and orexin B (hypocretin 2), a 28 amino acid peptide, are both derived from a common 130 amino acid precursor, prepro orexin. Orexin A and Orexin B stimulate food consumption when administered intracerebroventricularly to rats. Orexin gene expression in the brain is highly restricted to distinct populations of neurons located in specific hypothalamic regions, including the lateral hypothalamic area (LHA), a region implicated in feeding behaviour. Orexin A and orexin B bind to and activate two closely related G protein coupled receptors (GPCRs), termed Orexin 1 (OX1) and Orexin 2 (OX2) receptors. Dysfunction of the orexin peptide system has been linked to narcolepsy.

Synonyms

HCRT 1; HCRT; HCRT1; HCRT2; Hypocretin orexin neuropeptide precursor; Hypocretin 1; Hypocretin 2; Hypocretin A; Hypocretin; Hypocretin neuropeptide precursor; Hypocretin1; NRCLP1; Orexin A; Orexin; Orexin B; Orexin precursor; OrexinA; OX; PPORX; PPOX; PREPROOREXIN; OREX_HUMAN.

Gene ID

3060

Host

Rabbit

Cross Reactivity

Human

Target

Orexin A

Clonality

Polyclonal

Isotype

IgG

Conjugation

PerCP

Source

KLH conjugated synthetic peptide derived from human Orexin A

Applications

WB, IF (IHC-P)

Purification

Purified by Protein A.

Excitation Emission

482nm/677nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.biossantibodies.com/datasheets/bs-10376R-PerCP

Gene ID URL

3060

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