LDLR Polyclonal Antibody, PE Conjugated

Product Specifications

Background

Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. In case of HIV-1 infection, functions as a receptor for extracellular Tat in neurons, mediating its internalization in uninfected cells.

Synonyms

FH; FHC; LDLCQ2; Low-density lipoprotein receptor; LDL receptor; LDLR

Gene ID

3949

Swiss Prot

P01130

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse

Immunogen

781-860/860

Target

LDLR

Clonality

Polyclonal

Isotype

IgG

Conjugation

Source

KLH conjugated synthetic peptide derived from human LDL-R

Applications

WB, FCM, IF (IHC-P)

Purification

Purified by Protein A.

Excitation Emission

496,564nm/578nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

3949

Predicted Cross Reactivity

Rat, Dog, Cow, Pig, Horse, Rabbit, GuineaPig

Cross Reactivity Details

Hamster

Curated Selection

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