ICOS ligand Recombinant Antibody
Product Specifications
Background
Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.
Synonyms
B7H2; B7RP1; CD275; GL50; ICOSL; Icoslg; LICOS.
Gene ID
23308
Swiss Prot
O75144
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human
Target
ICOS ligand
Clonality
Recombinant
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human ICOS ligand
Applications
WB
Purification
Purified Polyclonal A
Concentration
Lot dependent
Dilution
WB (1:300-5000)
Buffer
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
23308
Isotype
IgG
Curated Selection
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