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Mer-NF5003F

Product Specifications

CAS Number

149598-70-9

Target

Virus Protease|||HSV

Related Pathways

Microbiology/Virology

Bioactivity

Mer-NF5003F (Stachybotrydial; F 1839M) is a sesquiterpene isolated from Stachybotrys, effective in inhibiting avian myeloblastosis virus (AMV) protease with an IC50 of 7.8 ?M. It also inhibits sialyltransferases ST6N, ST3O, and ST3N with IC50 values of 0.61, 6.7, and 10 ?g/mL, respectively, and fucosyltransferase with an IC50 of 11.3 ?g/mL. Additionally, Mer-NF5003F exhibits in vitro activity against herpes simplex virus HSV-1 (IC50=4.32 ?g/mL) and multi-drug-resistant Plasmodium falciparum K1 strain (IC50=0.85 ?g/mL) .

Smiles

O=CC1=CC(O)=C2C(OC3(C2)C(C)CCC4C(C)(C)C(O)CCC43C)=C1C=O

Molecular Formula

C23H30O5

Molecular Weight

386.48

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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