Caspase 14 Recombinant Antibody, AbBy Fluor™ 350 Conjugated

Product Specifications

Background

Non-apoptotic caspase involved in epidermal differentiation. Is the predominant caspase in epidermal stratum corneum.Seems to play a role in keratinocyte differentiation and is required for cornification. Regulates maturation of the epidermis by proteolytically processing filaggrin.In vitro has a preference for the substrate [WY]-X-X-D motif and is active on the synthetic caspase substrate WEHD-ACF.

Synonyms

CASP14; Caspase-14; Caspase 14; MICE; CASP-14.

Gene ID

23581

Swiss Prot

P31944

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human

Target

Caspase 14

Clonality

Recombinant

Conjugation

AbBy Fluor™ 350

Source

KLH conjugated synthetic peptide derived from human Caspase 14

Applications

WB, IF, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

346nm/442nm

Concentration

Lot dependent

Dilution

WB (1:300-5000), IF (), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Mouse, Rat

Gene ID URL

23581

Isotype

IgG

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