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Prox1 Polyclonal Antibody, PE Conjugated

Product Specifications

Background

Transcription factor involved in developmental processes such as cell fate determination, gene transcriptional regulation and progenitor cell regulation in a number of organs. Plays a critical role in embryonic development and functions as a key regulatory protein in neurogenesis and the development of the heart, eye lens, liver, pancreas and the lymphatic system. Involved in the regulation of the circadian rhythm. Represses: transcription of the retinoid-related orphan receptor RORG, transcriptional activator activity of RORA and RORG and the expression of RORA/G-target genes including core clock components: ARNTL/BMAL1, NPAS2 and CRY1 and metabolic genes: AVPR1A and ELOVL3.

Synonyms

Prospero homeobox protein 1; Homeobox prospero-like protein PROX1; PROX-1; PROX1

Gene ID

5629

Swiss Prot

Q92786

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Rat

Immunogen

151-250/737

Target

Prox1

Clonality

Polyclonal

Conjugation

PE

Source

KLH conjugated synthetic peptide derived from human Prox-1

Applications

WB, FCM, IF (IHC-P)

Purification

Purified by Protein A.

Excitation Emission

496,564nm/578nm

Concentration

1ug/ul

Dilution

WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Mouse, Dog, Cow, Pig, Horse, Rabbit

Gene ID URL

5629

Isotype

IgG

Curated Selection

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