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IL21 Polyclonal Antibody, Cy3 Conjugated

Product Specifications

Background

Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG (1) and IgG (3) in B-cells (By similarity) . May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation.

Synonyms

Za11; IL-21; CVID11; Interleukin-21; IL21

Gene ID

59067

Swiss Prot

Q9HBE4

Cellular Locus

Secreted

Host

Rabbit

Cross Reactivity

Human

Immunogen

65-155/155

Target

IL21

Clonality

Polyclonal

Conjugation

Cy3

Source

KLH conjugated synthetic peptide derived from human IL-21

Applications

WB, IF (IHC-P)

Purification

Purified by Protein A.

Excitation Emission

512,550nm/570,615nm

Concentration

1ug/ul

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Mouse, Rat, Dog, Cow, Pig

Gene ID URL

59067

Isotype

IgG

Curated Selection

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