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NR1D1 Recombinant Antibody

Product Specifications

Background

This gene encodes a transcription factor that is a member of the nuclear receptor subfamily 1. The encoded protein is a ligand-sensitive transcription factor that negatively regulates the expression of core clock proteins. In particular, this protein represses the circadian clock transcription factor aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL) . This protein may also be involved in regulating genes that function in metabolic, inflammatory and cardiovascular processes.

Synonyms

Nuclear receptor subfamily 1 group D member 1; Rev-erbA-alpha; V-erbA-related protein 1; EAR-1; NR1D1; EAR1; HREV; THRAL.

Gene ID

9572

Swiss Prot

P20393

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse

Target

NR1D1

Clonality

Monoclonal

Isotype

IgG

Clone

6D1

Conjugation

Unconjugated

Source

Recombinant protein within human NR1D1 aa 500 to the C-terminus

Applications

WB, IHC-P, IHC-F, IF

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500), IF ()

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Gene ID URL

9572

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