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KLF4 Recombinant Antibody

Product Specifications

Background

Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.

Synonyms

Krueppel-like factor 4, Epithelial zinc finger protein EZF, Gut-enriched krueppel-like factor, KLF4

Gene ID

9314

Swiss Prot

O43474

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

KLF4

Clonality

Recombinant

Isotype

IgG

Conjugation

Unconjugated

Source

Human KLF4 between 1 to 500 amino acids

Applications

WB, IHC-P, IHC-F, IF, Flow-Cyt, ICC/IF

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), IHC-P (1:200-400), IHC-F (1:100-500), IF (), Flow-Cyt (1ug/Test), ICC/IF (1:50-100)

Buffer

0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

9314

Available Sizes

Frequently Asked Questions

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