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SGLT2 Antibody

The sodium/glucose cotransporter 2 (SGLT2) is a protein that in humans is encoded by the SLC5A2 gene. It is mapped to 16p11.2. This gene encodes a member of the sodium glucose cotransporter family which are sodium-dependent glucose transport proteins. The encoded protein is the major cotransporter involved in glucose reabsorption in the kidney. Mutations in this gene are associated with renal glucosuria. Two transcript variants, one protein-coding and one not, have been found for this gene.

Product Specifications

Specifications

Western blot: 0.1-0.5 µg/mL, Immunohistochemistry (FFPE) : 0.5-1 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL

UniProt

P31639

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Amino acids A15-N656 from the human protein were used as the immunogen for the SGLT2 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, IHC-P, FACS, Direct ELISA

Purity

Affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide

Limitations

This SGLT2 antibody is available for research use only.

Storage Conditions

Store the SGLT2 antibody at -20°C.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the SGLT2 antibody should be determined by the researcher.

Image Legend

Western blot testing of 1) human HL-60, 2) human ThP-1, 3) rat kidney, 4) rat spleen, 5) rat lung, 6) mouse kidney, 7) mouse spleen and 8) mouse lung lysate with SGLT2 antibody. Predicted molecular weight ~73 kDa.

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