Idelalisib (CAL-101)
Product Specifications
CAS Number
870281-82-6
Synonyms
GS-1101
SKU
C08373-10mg
Target
PI3K
Applications
PI3K/Akt/mTOR
Smiles
CCC (C1=NC2=C (C (=CC=C2) F) C (=O) N1C3=CC=CC=C3) NC4=NC=NC5=C4NC=N5
Molecular Formula
C22H18FN7O
Additionnal Information
Idelalisib (CAL-101) is a selective p110δ inhibitor with IC50 of 2.5 nM in cell-free assays; shown to have 40- to 300-fold greater selectivity for p110δ than p110α/β/γ, and 400- to 4000-fold more selectivity to p110δ than C2β, hVPS34, DNA-PK and mTOR. Idelalisib also stimulates autophagy.
Storage Conditions
2 years -80 in solvent
Available Sizes
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