Zebrafish Srp54 Antibody / Signal recognition particle 54 kDa protein
Zebrafish Srp54 is an ortholog of the human SRP54 protein and exhibits strong sequence and functional conservation. In both zebrafish and humans, Srp54 contains a GTP binding domain and an M domain that recognizes and interacts with hydrophobic signal sequences. These conserved domains highlight the importance of Srp54 in protein translocation processes that are essential for the development and survival of eukaryotic cells. The use of a Zebrafish Srp54 antibody allows researchers to detect and study the distribution and expression of Srp54 during early development and in various tissues. Such antibodies are valuable for western blot, immunohistochemistry, and immunofluorescence applications, providing insights into the role of the SRP pathway in protein targeting. A Zebrafish Srp54 antibody can also be used to analyze the effects of genetic mutations or experimental treatments on protein translocation and endoplasmic reticulum function. There are no confirmed isoforms of zebrafish Srp54, and its function appears to be highly conserved across vertebrate species. By using a high-quality Zebrafish Srp54 antibody, researchers can explore the essential roles of the signal recognition particle pathway in protein sorting and its relevance to human biology and disease.
Product Specifications
Specifications
Western Blot: 0.5-1 µg/mL
UniProt
Q7ZVN5
Host
Rabbit
Reactivity
Zebrafish
Immunogen
E. coli-derived zebrafish Srp54 recombinant protein (amino acids M1-K433) was used as the immunogen for the Zebrafish Srp54 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB
Purity
Antigen affinity chromatography
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Limitations
This Zebrafish Srp54 antibody is available for research use only.
Storage Conditions
Product Datasheet
http://www.nsjbio.com/tds-pdf/zebrafish-srp54-antibody-signal-recognition-particle-54-kda-protein-rz1316
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Zebrafish Srp54 antibody should be determined by the researcher.
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