Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Human IL-17 RC (21-465) Protein, Fc Tag (MALS verified)

Interleukin-17 receptor C (IL-17 RC), also known as IL17Rhom, IL-17RL, is the receptor for IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RA. IL-17A activity is inhibited by IL-17RA, IL-17F is inhibited by IL-17RC, and a combination of soluble IL-17RA/IL-17RC receptors is required for inhibition of the IL-17F/IL-17A activity. Furthermore, activation of IL17RC can lead to the induction of expression of inflammatory chemokines and cytokines such as CXCL1.

Product Specifications

Background

Interleukin-17 receptor C (IL-17 RC), also known as IL17Rhom, IL-17RL, is the receptor for IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RA. IL-17A activity is inhibited by IL-17RA, IL-17F is inhibited by IL-17RC, and a combination of soluble IL-17RA/IL-17RC receptors is required for inhibition of the IL-17F/IL-17A activity. Furthermore, activation of IL17RC can lead to the induction of expression of inflammatory chemokines and cytokines such as CXCL1.

Specifications

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 76 kDa. The protein migrates as 100-130 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Expression Region

Leu 21 - His 465

Target

IL-17 RC

Conjugation

Unconjugated

Tag

C-Fc

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

90%

Format

Powder

Buffer

50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5

Molecular Weight

76 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

100ug*1

Host or Source

HEK293

Species

Human

Protein ID

NP_703190.2

Preservative

Trehalose

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

S100A5 Antibody
A40322-50UG 50 µg

S100A5 Antibody

Ask
View Details
NDUFS4 Rabbit pAb
E47R3961 100 µL

NDUFS4 Rabbit pAb

Ask
View Details
ZNF71, NT (ZNF71, EZFIT, Endothelial zinc finger protein induced by tumor necrosis factor alpha, Zinc finger protein 71) (MaxLight 650) discontinued
044343-ML650 100 µL

ZNF71, NT (ZNF71, EZFIT, Endothelial zinc finger protein induced by tumor necrosis factor alpha, Zinc finger protein 71) (MaxLight 650) discontinued

Ask
View Details
SPCS2 Polyclonal Antibody
RD252301A-01 20 µL

SPCS2 Polyclonal Antibody

Ask
View Details
SPCS2 Polyclonal Antibody
RD252301A-02 60 μL

SPCS2 Polyclonal Antibody

Ask
View Details
SPCS2 Polyclonal Antibody
RD252301A-03 120 μL

SPCS2 Polyclonal Antibody

Ask
View Details