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PREPL Recombinant Rabbit Monoclonal Antibody [JE65-64]

The protein encoded by this gene belongs to the prolyl oligopeptidase subfamily of serine peptidases. Mutations in this gene have been associated with hypotonia-cystinuria syndrome, also known as the 2p21 deletion syndrome. Several alternatively spliced transcript variants encoding either the same or different isoforms have been described for this gene. Serine peptidase whose precise substrate specificity remains unclear. Does not cleave peptides after a arginine or lysine residue. Regulates trans-Golgi network morphology and sorting by regulating the membrane binding of the AP-1 complex. May play a role in the regulation of synaptic vesicle exocytosis.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

PPCEL_HUMAN antibody prepl antibody Prolyl endopeptidase-like antibody Prolylendopeptidase-like antibody putative prolyl oligopeptidase antibody

Abbreviation

PREPL

Swiss Prot

Q4J6C6 Human, Q8C167 Mouse, Q5HZA6 Rat

Cellular Locus

Cytoskeleton, Nucleus, cytosol, trans-Golgi network, Golgi apparatus.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Recombinant protein within human PREPL aa 621-720/727.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P

Positive Control

NIH/3T3 cell lysates, PC-12 cell lysates, rat hippocampus tissue, rat brain tissue, mouse hippocampus tissue, mouse brain tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500 ;IHC-P: 1:400

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 84 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes

Frequently Asked Questions

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