PREPL Recombinant Rabbit Monoclonal Antibody [JE65-64]
The protein encoded by this gene belongs to the prolyl oligopeptidase subfamily of serine peptidases. Mutations in this gene have been associated with hypotonia-cystinuria syndrome, also known as the 2p21 deletion syndrome. Several alternatively spliced transcript variants encoding either the same or different isoforms have been described for this gene. Serine peptidase whose precise substrate specificity remains unclear. Does not cleave peptides after a arginine or lysine residue. Regulates trans-Golgi network morphology and sorting by regulating the membrane binding of the AP-1 complex. May play a role in the regulation of synaptic vesicle exocytosis.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
PPCEL_HUMAN antibody prepl antibody Prolyl endopeptidase-like antibody Prolylendopeptidase-like antibody putative prolyl oligopeptidase antibody
Abbreviation
PREPL
Swiss Prot
Q4J6C6 Human, Q8C167 Mouse, Q5HZA6 Rat
Cellular Locus
Cytoskeleton, Nucleus, cytosol, trans-Golgi network, Golgi apparatus.
Host
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within human PREPL aa 621-720/727.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P
Positive Control
NIH/3T3 cell lysates, PC-12 cell lysates, rat hippocampus tissue, rat brain tissue, mouse hippocampus tissue, mouse brain tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500 ;IHC-P: 1:400
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 84 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Frequently Asked Questions
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