CD11a Antibody
Mouse Monoclonal to CD11a.
Product Specifications
Product Name Alternative
LFA-1, LFA1A, ITGAL
UniProt
P20701
Reactivity
Human
Immunogen
Human peripheral blood lymphocytes
Target
CD11a
Clonality
Monoclonal
Clone
MEM-83
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Purification
Purified by protein-A affinity chromatography.
Concentration
1 mg/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Functional application: The antibody MEM-83 directly induces the binding of T cells to purified ICAM-1. Using an in vitro-translated CDlla cDNA deletion series, the MEM-83 activation epitope was mapped to the "I" domain of the LFA-1 alpha subunit. The studies have therefore identified a novel LFA-1 activation epitope mapping to the I domain of LFA-1, which could play a role in the regulation of LFA-1 binding to ICAM-1. Flow cytometry: Recommended dilution: 1 μg/ml.
Tested Applications
FA, FC, IP
Preservative
Phosphate buffered saline (PBS), pH 7.4
Isotype
Mouse IgG1
Entrez
3683
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