AK2 Antibody

Product Specifications

Background

Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis.

NCBI Gene ID

204

Swiss Prot

P54819

Accession Number

P54819

Host

Rabbit

Reactivity

Human

Immunogen

This AK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-217 amino acids from the C-terminal region of human AK2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

26 kDa

Fragment

Rabbit Ig

Symbol

AK2

NCBI Official Name

Adenylate kinase 2, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03168}

NCBI Organism

Homo sapiens

Background Reference 01

Noma, T., et al., Biochim. Biophys. Acta 1395 (1) :34-39 (1998) .

Background Reference 02

Lee, Y., et al., J. Biochem. 123 (1) :47-54 (1998) .

Background Reference 03

Lee, Y., et al., Biochem. Mol. Biol. Int. 39 (4) :833-842 (1996) .

Background Reference 04

Bruns, G.A., et al., Biochem. Genet. 15 (5-6), 477-486 (1977) .

Other Product Names

Adenylate kinase 2, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03168}, AK 2 {ECO:0000255|HAMAP-Rule:MF_03168}, 2743 {ECO:0000255|HAMAP-Rule:MF_03168}, ATP-AMP transphosphorylase 2 {ECO:0000255|HAMAP-Rule:MF_03168}, ATP:AMP phosphotransferase {ECO:0000255|HAMAP-Rule:MF_03168}, Adenylate monophosphate kinase {ECO:0000255|HAMAP-Rule:MF_03168}, Adenylate kinase 2, mitochondrial, N-terminally processed {ECO:0000255|HAMAP-Rule:MF_03168}, AK2 {ECO:0000255|HAMAP-Rule:MF_03168}, ADK2