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LexA DNA Binding Region Rabbit Polyclonal Antibody

Product Specifications

Background

Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. Implicated in hydroxy radical-mediated cell death induced by hydroxyurea treatment.

Product Name Alternative

Lexa dna binding region

Gene Name

LexA

Gene ID

948544

Swiss Prot

P0A7C2

Host

Rabbit

Reactivity

Cyanobacteria

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB

Field of Research

Microbiology

Purification

Affinity Purification

Dilution

WB 1:500-1:1000

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Modification

Unmodified

Molecular Weight

Refer to figures

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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