LexA DNA Binding Region Rabbit Polyclonal Antibody
Product Specifications
Background
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. Implicated in hydroxy radical-mediated cell death induced by hydroxyurea treatment.
Product Name Alternative
Lexa dna binding region
Gene Name
LexA
Gene ID
948544
Swiss Prot
P0A7C2
Host
Rabbit
Reactivity
Cyanobacteria
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Microbiology
Purification
Affinity Purification
Dilution
WB 1:500-1:1000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Modification
Unmodified
Molecular Weight
Refer to figures
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
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