Growth Hormone Receptor Rabbit Polyclonal Antibody
Product Specifications
Background
Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway. The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. Isoform 2 up-regulates the production of GHBP and acts as a negative inhibitor of GH signaling.
Product Name Alternative
GHR; Growth hormone receptor; GH receptor; Somatotropin receptor
Gene Name
GHR
Gene ID
2690
Swiss Prot
P10912
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, ICC/IF, FC
Field of Research
Signal Transduction
Purification
Affinity Chromatography
Dilution
WB 1:500-1:1000, ICC/IF 1:50-1:200, FC 1:50-1:100
Form
Liquid
Buffer
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
Unmodified
Molecular Weight
Calculated MW: 72 kDa; Observed MW: 140 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
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