Phospho-HDAC6 (Ser22) Rabbit Polyclonal Antibody
Product Specifications
Background
Involved in the regulation of many cellular processes, including cell migration, immune synapse formation, viral infection, and degradation of misfolded proteins. HDAC6 binds to both poly-ubiquitinated misfolded proteins and dynein motors, facilitating the transport of misfolded proteins to the aggresome. Required for subsequent recruitment of the autophagic machinery and clearance of aggresomes from the cell. Plays a key role in the protection against the deleterious effects of pathological protein aggregation that occurs in various diseases.
Product Name Alternative
HDAC6; KIAA0901; JM21; Histone deacetylase 6; HD6
Gene Name
HDAC6
Gene ID
10013
Swiss Prot
Q9UBN7
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Epigenetics and Nuclear Signaling
Purification
Affinity Purification
Dilution
WB 1:500-1:1000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Modification
Phosphorylated
Molecular Weight
Calculated MW: 131 kDa; Observed MW: 131 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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