PPP3R1 antibody
Product Specifications
Background
Protein phosphatase 3 (PPP3, formerly PP2B, Calcineurin), a serine/ threonine protein phosphatase, is a heterodimer composed of one catalytic subunit (PPP3C, Calcineurin A) and one regulatory subunit (PPP3R, Calcineurin B). PPP3R has two isoforms, PPP3R1 and PPP3R2. PPP3Rl is ubiquitously expressed in different tissues and is coded by the PPP3R1 gene which was mapped recently to human chromosome 2. PPP3Rl has four functional calcium-binding sites.
Synonyms
Calcineurin subunit B type 1|Protein phosphatase 2B regulatory subunit 1|Protein phosphatase 3 regulatory subunit B alpha isoform 1|PPP3R1|CNA2|CNB
Gene ID
5534
UniProt
P63098
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
protein phosphatase 3 (formerly 2B), regulatory subunit B, alpha isoform
Target
PPP3R1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, IP, WB, IF
Field of Research
Immunology, Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100; IP: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
15 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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