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PPP3R1 antibody

Product Specifications

Background

Protein phosphatase 3 (PPP3, formerly PP2B, Calcineurin), a serine/ threonine protein phosphatase, is a heterodimer composed of one catalytic subunit (PPP3C, Calcineurin A) and one regulatory subunit (PPP3R, Calcineurin B) . PPP3R has two isoforms, PPP3R1 and PPP3R2. PPP3Rl is ubiquitously expressed in different tissues and is coded by the PPP3R1 gene which was mapped recently to human chromosome 2. PPP3Rl has four functional calcium-binding sites.

Synonyms

Calcineurin subunit B type 1|Protein phosphatase 2B regulatory subunit 1|Protein phosphatase 3 regulatory subunit B alpha isoform 1|PPP3R1|CNA2|CNB

Gene ID

5534

UniProt

P63098

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Protein phosphatase 3 (formerly 2B), regulatory subunit B, alpha isoform

Target

PPP3R1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, IHC, IP, WB, IF

Field of Research

Immunology, Signal Transduction, Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100; IP: 1:50 - 1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

15 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, IHC, IP, WB, IF

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